How do sense and anti-sense RNAs function?
Ans.
Sense and antisense RNAs function in the following ways:
-
Sense RNA:
-
Sense RNA corresponds directly to the coding strand of DNA.
-
It carries the same sequence as the mRNA that will be translated into proteins.
-
Sense RNA is transcribed by RNA polymerase from the template (antisense) strand of DNA during transcription.
-
It serves as the template for protein synthesis during translation in the cytoplasm.
-
-
Antisense RNA:
-
Antisense RNA has a complementary sequence to the sense RNA or mRNA.
-
It is typically synthesized artificially or naturally to target specific mRNA molecules.
-
Antisense RNA can bind to complementary sequences in mRNA, forming RNA duplexes.
-
Formation of RNA duplexes can interfere with mRNA translation, leading to inhibition or degradation of the target mRNA.
-
Antisense RNA technology is used to regulate gene expression, modulate protein levels, and develop therapeutic interventions.
-
